Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-GEOD-11281

ABSTRACT: Transcription profiling by array of human peripheral blood mononuclear cells treated with staphylococcal superantigens SEB or SEI against untreated controls

OTHER RELATED OMICS DATASETS IN: PRJNA106687

PROVIDER: E-GEOD-11281 | ExpressionAtlas | 2014-09-18

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-GEOD-11281-analysis-methods.tsv	Tabular
	E-GEOD-11281-atlasExperimentSummary.Rdata	Rdata
	E-GEOD-11281-configuration.xml	Xml
	E-GEOD-11281-percentile-ranks.tsv	Tabular
	E-GEOD-11281.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 79

Similar Datasets

Sen2020 - Metabolic alteration in PBMCs associated with type 1 diabetes

Project description:Genome-Scale draft model for Human Peripheral Blood Mononuclear Cells (PBMCs). A GEM for PBMCs was developed by applying the INIT algorithm on Human Metabolic Reconstruction (HMR 2.0) as a template model. GEMs were contextualised/ constrained for different conditions using expression datasets. The gene/transcript expression data obtained from PBMCs of Type 1 Diabetes progressors, non-progressors, and healthy controls were employed to score each reaction of HMR 2.0. For further detail please refer to Electronic Supplementary Information of Sen et.al, Metabolic alterations in immune cells associate with progression to type 1 diabetes, Diabetologia, 15/01/2020, (https://doi.org/10.1007/s00125-020-05107-6).

2020-03-11 | MODEL1905270001 | BioModels

Assessment of the effect of RNase A-treated Enterococcus feacalis strain EC-12(EC-12) or untreated EC-12 on transcriptome profiles in human peripheral blood mononuclear cells

Project description:Whole blood was collected from healthy adult and peripheral blood mononuclear cells (PBMC) were isolated. PBMCs were cultured in medium or stimulated with RNase treated EC-12 or untreated EC-12 for 6hours. Then transcriptome profiles in PBMC were obtained.

2019-06-25 | GSE126161 | GEO

Expression profiles of PBMC from multiple sclerosis patients

Project description:Affymetrix GeneChip Human Gene 1.0 ST Array was applied to compare the expression profiles in peripheral blood mononuclear cells(PBMC) between healthy controls and multiple sclerosis patients(MS pt). It suggested that certain genes involved in apoptosis pathway have been changed regulated in PBMC from MS pt.

2011-03-01 | GSE23832 | GEO

Protein expression of PBMCs treated with ITPRIPL1

Project description:Purified human ITPRIPL1-extracellular domain (ITPRIPL1-ECD) protein or PBS was added to human peripheral blood mononuclear cells (PBMCs) as a widely used source of immune cells and treated for 18 hours under 37℃, 5% CO2 in separate 1.5 ml EP tubes (n=3 independent samples for each condition)

2024-03-10 | PXD050518 |

Effect of nicotinamide mononucleotide on gene expression of CD4+ T cells with HIV-1 infection or mock infection

Project description:To investigate the effect of nicotinamide mononucleotide (NMN) on CD4+ T cells, primary human CD4+ T cells purified from peripheral blood mononuclear cells of healthy donors were treated without or with NMN. Expression profiling analysis on either host gene or viral gene was performed using data obtained from bulk RNA-seq of NMN-treated and untreated (control) CD4+ T cells at 48 hours post treatment and/or post infection.

2023-10-27 | GSE234308 | GEO

Human germline biallelic complete NFAT1 deficiency causes the triad of joint contractures, osteochondromas, and susceptibility to B cell malignancy [Single]

Project description:We isolated peripheral blood mononuclear cells from whole blood from an NFAT1 deficient patient and 5 healthy controls. Cells were either treated with PMA (50ng/mL) + 1uM Ionomycin for 4 hours, or left untreated. Cells were then isolated in nanowells, and incubated with single mRNA-capture beads. mRNA from these beads were used for library preparation and sequenced. Raw counts were used for clustering analysis and differential expression. This analysis pointed to defects in NFAT1 deficient patient's B-cells and T-cells that could be contributing the observed B-cell malignancy

2023-02-20 | GSE193410 | GEO

Genome-wide Expression Profiling in Irritable Bowel Syndrome

Project description:Differential gene expression profiling in peripheral blood mononuclear cells (PBMCs) was performed using Human Transcriptome Array 2 (HTA2)

2016-12-31 | GSE63379 | GEO

Homo sapiens

Project description:Human Peripheral blood monocytes untreated or treated with CXCL12

| PRJNA132499 | ENA

Expression data from peripheral blood mononuclear cell in patients with type 1 diabetes compared with normal controls

Project description:Type 1 diabetes mellitus (T1D) is a common autoimmune disease mediated by autoimmune attack against pancreatic b cells.Dys-regualtion of the component of peripheral blood mononuclear cells (PBMCs), including T-cells and B-cells, and smaller amounts of NK cells and dendritic cells, have all been implicated in this process This study sought to identify T1D associated differently expressed genes in the peripheral blood mononuclear cell (PBMC). Peripheral blood mononuclear of newly diagnosed type1 diabetes patients and normal controls were purified by LymphoprepTm gradient purification according to the manufacturer’s instructions (Axis-Shield PoC AS, Oslo, Norway) for futher microarray analysis.

2014-08-16 | E-GEOD-55098 | biostudies-arrayexpress

Homo sapiens

Project description:Peripheral blood mononuclear cells treated with a CDK inhibitor

| PRJNA122945 | ENA