Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-GEOD-21944

ABSTRACT: Transcription profiling by array of mouse retina from wild type and ERR-beta knock out strains

OTHER RELATED OMICS DATASETS IN: PRJNA127231

PROVIDER: E-GEOD-21944 | ExpressionAtlas | 2014-12-19

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-GEOD-21944-analysis-methods.tsv	Tabular
	E-GEOD-21944-atlasExperimentSummary.Rdata	Rdata
	E-GEOD-21944-configuration.xml	Xml
	E-GEOD-21944-percentile-ranks.tsv	Tabular
	E-GEOD-21944.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 56

Similar Datasets

RNA-seq analysis of HSF1 knockout on LiCl treatment

Project description:Heat shock transcription factor 1(HSF1) is an important transcription factor which regulates the expression of a wide array of genes including heat shock proteins and oncogenes. Here, we report that HSF1 as a target of WNT/β-catenin signaling, regulates parts of target genes of WNT/β-catenin signaling. To explore the biological relevance of HSF1 activation to WNT/β-catenin signaling, we profiled gene expression of wild type mouse embryonic fibroblasts (WT MEF) and HSF1 knock out MEF (HSF1 KO MEF) before and after lithium chloride (LiCl) treatment which was a potent GSK3β inhibitor and increased the expression of β-catenin.

2020-08-31 | GSE151119 | GEO

Wild type and EGR2 knock-out mouse alveolar macrophages

Project description:Wild type and EGR2 knock-out mouse alveolar macrophages

| PRJNA750652 | ENA

SIRT6 regulates glucose metabolism and glutamatergic synapse in the mouse retina

Project description:Microarray analysis on total retinal RNA from 15 day old Sirt6 wild-type (WT) and knock-out (KO) mice. The retina is one of the major energy consuming tissues within the body. In this context, synaptic transmission between light-excited rod photoreceptors and downstream ON-bipolar neurons is a highly demanding energy consuming process. Sirtuin 6 (SIRT6), a NAD-dependent deacylase, plays a key role in regulating glucose metabolism. In this study, we demonstrate that SIRT6 is highly expressed in the retina, controlling levels of histone H3K9 and H3K56 acetylation. Notably, despite apparent normal histology, SIRT6 deficiency caused major retinal transmission defects concomitant to changes in expression of glycolytic genes and glutamate receptors, as well as elevated levels of apoptosis in inner retina cells. Our results identify SIRT6 as a critical modulator of retinal function, likely through its effects on chromatin. Microarray analysis of total retinal RNA from 15 day old Sirt6 wild-type (WT) and knock-out (KO) mice with 3 replicates in each condition using the Affymetrix Mouse Gene 2.1 ST array (transcript (gene) version).

2014-07-30 | E-GEOD-56563 | biostudies-arrayexpress

Halobacterium NRC-1 Growth curve and GTF perturbation

Project description:Total RNA was collected at 6 or 8 points throughout the growth curve of Halobacterium NRC1 for wild-type, non-native expression of general transcription factors and knock-out strains of general transcription factors. This RNA was hybridized against our standard reference RNA (wild-type OD600 0.5-0.6). Keywords: growth genetic modification

2007-02-23 | GSE6776 | GEO

Project description:DNM1L Knock-out VS Wild type

| PRJNA688401 | ENA

Mus musculus

Project description:Microarray of wild type, Shp2 knock-out, Pten knock-out and double knock-out erythroblasts

| PRJNA210300 | ENA

Project description:Transcriptomes analysis of wild type BCG and DosR knock out strains

| PRJNA753963 | ENA

Mus musculus

Project description:Mouse ureter: wild type vs miR-143/145 knock out

| PRJNA251871 | ENA

Gene expression of E. coli MG1655 wild type and rpoS knock-out strains

Project description:The role of rpoS gene in the formation of Escherichia coli biofilms were investigated. The gene expression was compared among E. coli MG1655 wild type strain and rpoS knock-out strain in the biofilms, the planktonic exponential phase, and the planktonic stationary phase. The analysis revealed that the wild type bilfilms (WBF) showed similar pattern of gene expression with the WT planktonic stationary phase (WS), whereas the rpoS knock-out biofilms (MBF) showed similar pattern of gene expression with the wild type planktonic exponential phase (WE). Genes involved in the energy metabolism and the flagella synthesis showed higher expression in the rpoS knock-out biofilms (MBF), but not in the wild type biofilms (WBF). Moreover, genes involved in the stress responses showed higher expression in the wild type biofilms (WBF), but not in the rpoS knock-out biofilms (MBF). Keywords: cell type comparison (biofilms vs planktonic cells, wild type vs rpoS knock-out strains)

2008-05-23 | GSE7885 | GEO

Gene expression profile of Otx2 KI and Crx KO retina at P12

Project description:To analyze the expression profile in the Otx2 knock-in (a knock-in mouse line expressing Otx2 from the Crx locus on chromosome 7) and Crx knockout retina, we performed a microarray analysis using wild-type (Crx +/+), Otx2 KI (Crx Otx2/Otx2) and Crx KO (Crx -/-) retina at P12.

2020-01-24 | GSE129443 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data