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E-GEOD-48191

ABSTRACT: The gene expression profiles of WT and NML-KO livers

OTHER RELATED OMICS DATASETS IN: PRJNA209130

PROVIDER: E-GEOD-48191 | ExpressionAtlas | 2015-07-17

REPOSITORIES: ExpressionAtlas

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Dataset's files

Source:

			Action	DRS
	E-GEOD-48191-analysis-methods.tsv	Tabular
	E-GEOD-48191-atlasExperimentSummary.Rdata	Rdata
	E-GEOD-48191-configuration.xml	Xml
	E-GEOD-48191-percentile-ranks.tsv	Tabular
	E-GEOD-48191.condensed-sdrf.tsv	Tabular

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1 - 5 of 44

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Project description:The gene expression profiles of WT and NML-KO livers

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The gene expression profiles of WT and NML-KO livers

Project description:To examine whether energy starvation caused by the increase in rRNA transcription affects liver metabolism, we compared the gene expression profiles of WT and NML-KO livers using Affymetrix microarray technology. We analyzed 5 livers of WT mice and 5 livers of NML-KO mice.

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Project description:The RNA-binding protein Snd1 can regulate gene expression through various mechanisms, including microRNA decay. Here we have investigated microRNA expression in livers of WT and Snd1 knockout (KO) mice

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Project description:To explore the potential targets of Bmi1 in the liver development of hepatic carcinogenesis, we assayed the gene expression level in the liver of Bmi1 knockout mice. We isolated the liver tissue of Bmi1 WT and KO mice around 6-8 weeks. Then we extracted total RNA and run the microarray detection. Gene expression in Bmi1 KO mouse livers was compared with that in Bmi1 WT mouse livers to screen potential targets of Bmi1.

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Project description:To identify genes regulated by FXR in mouse liver, we compared gene expression profiles in livers of FXR+/+ (wt) and liver-specific FXR KO (lKO) mice

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