Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-MTAB-1075

ABSTRACT: Transcriptional profiling by array of bone marrow and peripheral blood samples from patients with cytogenetically normal acute myeloid leukemia to study gene expression profiles associated with different levels of miR-3151 expression

PROVIDER: E-MTAB-1075 | ExpressionAtlas | 2025-01-23

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-MTAB-1075-analysis-methods.tsv	Tabular
	E-MTAB-1075-atlasExperimentSummary.Rdata	Rdata
	E-MTAB-1075-configuration.xml	Xml
	E-MTAB-1075-percentile-ranks.tsv	Tabular
	E-MTAB-1075.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 60

Similar Datasets

miR-3151 interplays with its host gene BAALC and independently impacts on outcome of patients with cytogenetically normal acute myeloid leukemia - expression microarray data

Project description:Recently, deep sequencing of melanoma and pediatric acute lymphoblastic leukemia samples identified a new microRNA - miR-3151 - embedded in intron 1 of the BAALC gene. MiR genes are located throughout the genome, but about one-third of mammalian miRs reside within introns of host genes. Some of these intronic miRs have been found to act in functional synergism with their host genes. These findings led us to hypothesize that miR-3151 could be overexpressed in patients with elevated BAALC levels and thus might contribute to the adverse prognostic impact of its host gene, either acting in concert with BAALC or perhaps even being the element predominantly responsible for the adverse outcome observed in BAALC overexpressing AML patients.Thus, we have measured miR-3151 and BAALC expression in a cohort of molecularly well characterized de novo CN-AML patients to assess the impact of miR-3151 expression alone and in combination with its host BAALC on outcome. microRNA expression profiles associated with miR-3151 expression in older patients with cytogenetically normal acute myeloid leukemia were derived using microarrays. The corresponding microRNA expression data can be found under accession number E-MTAB-1074.

2012-12-31 | E-MTAB-1075 | biostudies-arrayexpress

miR-3151 interplays with its host gene BAALC and independently impacts on outcome of patients with cytogenetically normal acute myeloid leukemia - microRNA microarray data

Project description:Recently, deep sequencing of melanoma and pediatric acute lymphoblastic leukemia samples identified a new microRNA - miR-3151 - embedded in intron 1 of the BAALC gene. MiR genes are located throughout the genome, but about one-third of mammalian miRs reside within introns of host genes. Some of these intronic miRs have been found to act in functional synergism with their host genes. These findings led us to hypothesize that miR-3151 could be overexpressed in patients with elevated BAALC levels and thus might contribute to the adverse prognostic impact of its host gene, either acting in concert with BAALC or perhaps even being the element predominantly responsible for the adverse outcome observed in BAALC overexpressing AML patients.Thus, we have measured miR-151 and BAALC expression in a cohort of molecularly well characterized de novo CN-AML patients to assess the impact of miR-3151 expression alone and in combination with its host BAALC on outcome. microRNA expression profiles associated with miR-3151 expression in older patients with cytogenetically normal acute myeloid leukemia were derived using microarrays. The corresponding affymetrix data can be found under accession number E-MTAB-1075.

2012-07-20 | E-MTAB-1074 | biostudies-arrayexpress

E-GEOD-21369

Project description:Gene expression profiles of interstitial lung disease (ILD) patients

2025-01-24 | E-GEOD-21369 | ExpressionAtlas

E-MTAB-5638

Project description:Systemic gene expression profiles in patients with ventilator-associated pneumonia

2025-01-23 | E-MTAB-5638 | ExpressionAtlas

E-GEOD-35008

Project description:Expression data from human hematopoietic stem and progenitor compartments from patients with acute myeloid leukemia with normal karyotype and healthy controls

2025-01-24 | E-GEOD-35008 | ExpressionAtlas

Expression profiles of acute myeloid leukemia patient samples

Project description:Expression profiles of acute myeloid leukemia patient samples. Blasts and mononuclear cells were purified from bone marrow or peripheral blood aspirates of acute myeloid patients. Samples contained 80-100 percent blast cells. Total RNA was extracted by lyses with guanidium isothiocyanate followed by cesium chloride gradient purification Keywords: other

2004-04-15 | GSE1159 | GEO

E-MTAB-8135

Project description:Global gene expression profiles of 10 gastric cancer (GC) samples and 10 gastric normal adjacent tissue (gNAT) samples

2025-01-16 | E-MTAB-8135 | ExpressionAtlas

Transcription profiling of human acute myeloid leukemia patient samples

2008-06-12 | E-GEOD-1159 | biostudies-arrayexpress

E-TABM-1208

Project description:Transcription profiling by array of patients with ASXL1 mutations in cytogenetically normal acute myeloid leukemia

2025-01-16 | E-TABM-1208 | ExpressionAtlas

E-GEOD-10746

Project description:Microarray analysis of oral punch biopsies from acute myeloid leukemia (AML) patients treated with chemotherapy

2025-01-16 | E-GEOD-10746 | ExpressionAtlas