Project description:The transcriptome of WT and Rarb KO hematopoietic stem cells (HSC) after 24h in vitro culture upon retinoid treatment was assessed by RNAseq.
Project description:Gene expression profiles of Cep135 wildtype and knockout E14.4 and E11.5 mouse embryonic neocortices. Gene expression profiles of in vitro E14.5 cortices-derived primary neurospheres are also included; in vitro samples listed as "12h" or "24h" depending on the duration of the in vitro culture from NPs isolation for incipient neurosphere formation and RNA isolation for RNAseq.
Project description:We analyzed the transcriptome of LT-HSCs sorted from wildtype and DERARE knockout mice. We aim at identifying differentially expressed genes and downstream signaling pathways associated with HSC defects in DERARE KO mice, and determining whether Wnt5a treatment could rescue the HSC defects in DERARE KO mice.
Project description:To unravel the molecular mechanism underlying miR-17∼92 costimulatory function, we performed RNA-seq on CD4+ T cells from mice lacking miR-17∼92 in T cell, wildtype mice and mice overexpressing miR-17∼92 in T cells, in naïve state or activated vitro for 24h and 48h.
Project description:We compared gene expression differences in Atxn1L knockout vs wildtype HSCs KO allele described in Pub Med ID: 22014525 HSCs were purified as Lineage-negative, Sca-1+ c-Kit+ (LSK), CD150+ and Side population from both Atxn1L-null and WT mice on C57Bl/6 background