Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-TABM-15

ABSTRACT: Transcription profiling of cancerous and non cancerous lung adenocarcinoma tissue. Tumour and normal samples from human lung carcinoma from 18 patients plus tumour only from 5 patients

PROVIDER: E-TABM-15 | ExpressionAtlas | 2025-01-16

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-TABM-15-analysis-methods.tsv	Tabular
	E-TABM-15-atlasExperimentSummary.Rdata	Rdata
	E-TABM-15-configuration.xml	Xml
	E-TABM-15-configuration.xml.beforeQC	Xml
	E-TABM-15-percentile-ranks.tsv	Tabular

Items per page:

1 - 5 of 72

Similar Datasets

E-MEXP-3715

Project description:Transcription profiling by array of paired tumour and normal samples from colorectal cancer patients

2025-01-22 | E-MEXP-3715 | ExpressionAtlas

E-GEOD-81089

Project description:RNA-seq of 199 non-small cell lung carcinoma patients and 19 paired normal lung tissues

2025-01-24 | E-GEOD-81089 | ExpressionAtlas

Transcription profiling of cancerous and non cancerous lung adenocarcinoma tissue. Tumour and normal samples from human lung carcinoma from 18 patients plus tumour only from 5 patients

Project description:Comparison of gene expression of cancerous and non cancerous lung adenocarcinoma tissue. Tumour and normal samples from 18 patients plus tumour only from 5 patients.

2007-04-01 | E-TABM-15 | biostudies-arrayexpress

Quantification of metabolic enzymes in SCLC, NSCLC-Ad. and NSCLC-Sq.

Project description:For the iMPQAT analysis, we retrospectively collected frozen samples of the tumors from 36 patients with lung adenocarcinoma (n = 12), squamous cell carcinoma (n = 12) and LD-SCLC[TG1] (n = 12) who had undergone surgical resection at Kyushu University Hospital between January 2012 and July 2018. Among 12 patients with SCLC, frozen samples of the normal lung tissue were available in 6 patients.

2023-07-01 | PXD035054 | JPOST Repository

Quantitative proteomics identifies tumour matrisome signatures in patients with non-small cell lung cancer

Project description:The composition and remodelling of the extracellular matrix (ECM) are important factors in the development and progression of cancers, and the ECM is implicated in promoting tumour growth and restricting anti-tumour therapies through multiple mechanisms. The characterisation of differences in ECM composition between normal and diseased tissues may aid in identifying novel diagnostic markers, prognostic indicators and therapeutic targets for drug development. Using tissue from non-small cell lung cancer (NSCLC) patients undergoing curative intent surgery, we characterised quantitative tumour-specific ECM proteome signatures by mass spectrometry, identifying 161 matrisome proteins differentially regulated between tumour tissue and nearby non-malignant lung tissue. We defined a collagen hydroxylation functional protein network that is enriched in the lung tumour microenvironment. We validated two novel putative extracellular markers of NSCLC, the collagen cross-linking enzyme peroxidasin and a disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAMTS16), for discrimination of malignant and non-malignant lung tissue. These proteins were up-regulated in lung tumour samples, and high PXDN and ADAMTS16 gene expression was associated with shorter survival of lung adenocarcinoma and squamous cell carcinoma patients, respectively. These data reveal tumour matrisome signatures in human NSCLC.

2023-06-16 | PXD041066 | Pride

E-GEOD-48397

Project description:Expression data from (mouse) normal lung fibroblasts and carcinoma-associated fibroblasts

2015-07-15 | E-GEOD-48397 | ExpressionAtlas

Non Small Cell Lung Cancer

Project description:This series contain 36 samples obtained from human lung tissue and includes the following: 7 Adenocarcinoma samples. 16 Squamous cell carcinoma samples. 1 AdenoSquamous sample. 2 Renal Metastasis. 1 Colon metastasis. 7 normal lung tissue adjacent to the tumors. 2 commercial normal lung RNA. Keywords = Lung Keywords = Non Small Cell Lung Cancer Keywords = Adenocarcinoma Keywords = Squamous Cell Carcinoma Keywords = Normal Lung. Keywords: other

2005-07-20 | GSE1987 | GEO

The single cell transcriptional landscape of human lung adenocarcinoma (primary tumours and metastases)

Project description:By transcriptionally profiling single cells from patients spanning different stages of lung adenocarcinoma progression, we provide evidence of epithelial regeneration in untreated primary tumours and a continuum of phenotypic states spanning key stages of embryonic development and lung morphogenesis in metastases. We transcriptionally profiled 41,384 single cells obtained from fresh surgical human samples taken from non-tumour-involved lung (n = 4), primary lung adenocarcinomas (n = 8; 7 untreated and 1 post neo-adjuvant chemotherapy), as well as brain (n = 3), bone (n = 1), and adrenal (n = 1) lung adenocarcinoma metastases. These samples were derived from patients spanning various stages of tumour progression without enrichment for a specific cell type, such that the entire tumour and its microenvironment were sampled in an unbiased manner. Data from all patients were merged to create a global cell atlas of the normal lung, primary tumours, and metastases.

2020-01-14 | GSE123902 | GEO

E-GEOD-60052

Project description:RNA-seq of primary tumors from 79 small cell lung cancer patients and 7 normal lung tissue

2025-01-24 | E-GEOD-60052 | ExpressionAtlas

E-GEOD-6631

Project description:Transcription profiling of human head and neck paired diseased squamous cell carcinoma samples vs normal

2025-01-24 | E-GEOD-6631 | ExpressionAtlas