Ontology highlight
ABSTRACT:
SUBMITTER: Kun Yang
PROVIDER: BIOMD0000000106 | BioModels | 2024-09-02
REPOSITORIES: BioModels
Items per page: 1 - 5 of 16 |
PLoS computational biology 20070207 3
Drug molecules not only interact with specific targets, but also alter the state and function of the associated biological network. How to design drugs and evaluate their functions at the systems level becomes a key issue in highly efficient and low-side-effect drug design. The arachidonic acid metabolic network is the network that produces inflammatory mediators, in which several enzymes, including cyclooxygenase-2 (COX-2), have been used as targets for anti-inflammatory drugs. However, neither ...[more]