Ontology highlight
ABSTRACT:
SUBMITTER: Michael Schubert
PROVIDER: BIOMD0000000361 | BioModels | 2024-09-02
REPOSITORIES: BioModels
Items per page: 1 - 5 of 11 |
European journal of biochemistry 20020401 8
We have analyzed several mathematical models that describe inhibition of the factor VIIa-tissue factor complex (VIIa-TF) by tissue factor pathway inhibitor (TFPI). At the core of these models is a common mechanism of TFPI action suggesting that only the Xa-TFPI complex is the inhibitor of the extrinsic tenase activity. However, the model based on this hypothesis could not explain well all the available experimental data. Here, we show that a good quantitative description of all experimental data ...[more]