Ontology highlight
ABSTRACT:
SUBMITTER: Johannes Meyer
PROVIDER: BIOMD0000000812 | BioModels | 2024-09-02
REPOSITORIES: BioModels
Items per page: 5 1 - 5 of 12 |
Galante Amanda A Tamada Koji K Levy Doron D
Bulletin of mathematical biology 20110609 1
The surface protein B7-H1, also called PD-L1 and CD274, is found on carcinomas of the lung, ovary, colon, and melanomas but not on most normal tissues. B7-H1 has been experimentally determined to be an antiapoptotic receptor on cancer cells, where B7-H1-positive cancer cells have been shown to be immune resistant, and in vitro experiments and mouse models have shown that B7-H1-negative tumor cells are significantly more susceptible to being repressed by the immune system. We derive a new mathema ...[more]