Shin2016 - Unveiling Hidden Dynamics of Hippo Signalling
Ontology highlight
ABSTRACT:
SUBMITTER: 
Johannes Meyer
PROVIDER: BIOMD0000000832 | BioModels | 2024-09-02
REPOSITORIES: BioModels
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| BIOMD0000000832?filename=Shin2016.cps | Other | |||
| BIOMD0000000832?filename=Shin2016.sedml | Other | |||
| BIOMD0000000832?filename=Shin2016.xml | Xml |
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Publications
Unveiling Hidden Dynamics of Hippo Signalling: A Systems Analysis.
Shin Sung-Young SY Nguyen Lan K LK
Genes 20160805 8
The Hippo signalling pathway has recently emerged as an important regulator of cell apoptosis and proliferation with significant implications in human diseases. In mammals, the pathway contains the core kinases MST1/2, which phosphorylate and activate LATS1/2 kinases. The pro-apoptotic function of the MST/LATS signalling axis was previously linked to the Akt and ERK MAPK pathways, demonstrating that the Hippo pathway does not act alone but crosstalks with other signalling pathways to coordinate ...[more]
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To the extent possible under law, all copyright and related or
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