Viertel2019 - A Computational model of the mammalian external tufted cell
Ontology highlight
ABSTRACT:
SUBMITTER: 
Johannes Meyer
PROVIDER: BIOMD0000000844 | BioModels | 2024-09-02
REPOSITORIES: BioModels
Dataset's files
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Publications
A Computational model of the mammalian external tufted cell.
Viertel Ryan R Borisyuk Alla A
Journal of theoretical biology 20181002
We introduce a novel detailed conductance-based model of the bursting activity in external tufted (ET) cells of the olfactory bulb. We investigate the mechanisms underlying their bursting, and make experimentally-testable predictions. The ionic currents included in the model are specific to ET cells, and their kinetic and other parameters are based on experimental recordings. We validate the model by showing that its bursting characteristics under various conditions (e.g. blocking various curren ...[more]
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Project description:Wang2008 - Mimicking the inhibitory effect of
riluzole on membrane conductance in skeletal fibres
This model is described in the article:
Riluzole-induced block of
voltage-gated Na+ current and activation of BKCa channels in
cultured differentiated human skeletal muscle cells.
Wang YJ, Lin MW, Lin AA, Wu
SN.
Life Sci. 2008 Jan; 82(1-2):
11-20
Abstract:
Riluzole is known to be of therapeutic use in the management
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Western blotting revealed the protein expression of
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This model is hosted on
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BIOMD0000000693.
To cite BioModels Database, please use:
Chelliah V et al. BioModels: ten-year
anniversary. Nucl. Acids Res. 2015, 43(Database
issue):D542-8.
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