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Koduru2022 - Lactococcus lactis subsp. cremoris NZ9000


ABSTRACT: GEM reconstruction of Lactococcus lactis subsp. cremoris NZ9000

SUBMITTER: Yi Qing Lee  

PROVIDER: MODEL2210190009 | BioModels | 2023-11-27

REPOSITORIES: BioModels

Dataset's files

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MODEL2210190009?filename=FROG.omex Other
MODEL2210190009?filename=Koduru2022_LcLt.xml Xml
MODEL2210190009?filename=MemoteReport.html Other
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Publications

Systematic evaluation of genome-wide metabolic landscapes in lactic acid bacteria reveals diet- and strain-specific probiotic idiosyncrasies.

Koduru Lokanand L   Lakshmanan Meiyappan M   Lee Yi Qing YQ   Ho Pooi-Leng PL   Lim Pei-Yu PY   Ler Wei Xuan WX   Ng Say Kong SK   Kim Dongseok D   Park Doo-Sang DS   Banu Mazlina M   Ow Dave Siak Wei DSW   Lee Dong-Yup DY  

Cell reports 20221201 10


Lactic acid bacteria (LAB) are well known to elicit health benefits in humans, but their functional metabolic landscapes remain unexplored. Here, we analyze differences in growth, intestinal persistence, and postbiotic biosynthesis of six representative LAB and their interactions with 15 gut bacteria under 11 dietary regimes by combining multi-omics and in silico modeling. We confirmed predictions on short-term persistence of LAB and their interactions with commensals using cecal microbiome abun  ...[more]

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