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Rong2020 - Grover-Bace: Prediction of Beta-secretase 1 (BACE-1) inhibition.

ABSTRACT: Prediction of Beta-secretase 1 (BACE-1) inhibition. BACE-1 is expressed mainly in neurons and has been involved in the development of Alzheimer's disease. This model has been trained on the BACE dataset from MoleculeNet using the GROVER transformer. Model Type: Predicitive machine learning model. Model Relevance: Probability that the molecule is a BACE-1 inhibitor. Model Encoded by: Amna Ali (Ersilia) Metadata Submitted in BioModels by: Zainab Ashimiyu-Abdusalam Implementation of this model code by Ersilia is available here: https://github.com/ersilia-os/eos2mhp

SUBMITTER: Zainab Ashimiyu-Abdusalam

PROVIDER: MODEL2406050003 | BioModels | 2024-06-05

REPOSITORIES: BioModels

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