Ontology highlight
ABSTRACT:
SUBMITTER: Christine Nardini
PROVIDER: MODEL2406110001 | BioModels | 2024-06-17
REPOSITORIES: BioModels
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MODEL2406110001?filename=MechanotransductionSBMLPathway.xml | Xml |
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Wei Linyu L Mousawi Fatema F Li Dongliang D Roger Sébastien S Li Jing J Yang Xuebin X Jiang Lin-Hua LH
Frontiers in pharmacology 20191106
Organs and tissues and their constituent cells are physiologically submitted to diverse types of mechanical forces or stress, one common sequence of which is release of intracellular ATP into extracellular space. Extracellular ATP is a well-established autocrine or paracrine signaling molecule that regulates multiple cell functions and mediates cell-to-cell communications <i>via</i> activating the purinergic P2 receptors, more specifically, ligand-gated ion channel P2X receptors and some of the ...[more]