Models

Dataset Information

0

Ajay_Bhalla_2007_PKM

ABSTRACT: This is a non-bistable model of ERKII signaling that also incorporates PKM synthesis triggered by Ca influx. It is a simplified variant of the model of Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.

SUBMITTER: Sharat Vayttaden  

PROVIDER: MODEL9147232940 | BioModels | 2005-01-01

REPOSITORIES: BioModels

Json Xml

Dataset's files

Source:
Action DRS
MODEL9147232940?filename=MODEL9147232940-biopax2.owl Owl
MODEL9147232940?filename=MODEL9147232940-biopax3.owl Owl
MODEL9147232940?filename=MODEL9147232940.m Other
MODEL9147232940?filename=MODEL9147232940.pdf Pdf
MODEL9147232940?filename=MODEL9147232940.png Other
Items per page:
1 - 5 of 11
altmetric image

Publications

A propagating ERKII switch forms zones of elevated dendritic activation correlated with plasticity.

Ajay Sriram M SM   Bhalla Upinder S US  

HFSP journal 20070418 1

Strong inputs to neurons trigger complex biochemical events leading to synaptic plasticity. These biochemical events occur at many spatial scales, ranging from submicron dendritic spines to signals that propagate hundreds of microns from dendrites to the nucleus. ERKII is an important signaling molecule that is involved in many aspects of plasticity, including local excitability, communication with the nucleus, and control of local protein synthesis. We observed that ERKII activation spreads lon  ...[more]

Similar Datasets

Models Ajay_Bhalla_2007_Bistable
2005-01-01 | MODEL9147091146 | BioModels
Models Ajay_Bhalla_2004_Feedback_Tuning
2005-01-01 | MODEL9089914876 | BioModels
Models Ajay_Bhalla_2004_PKM_Tuning
2005-01-01 | MODEL9089491423 | BioModels
Models Ajay_Bhalla_2004_PKM_MKP3_Tuning
2005-01-01 | MODEL9089538076 | BioModels
Transcriptomics Transcriptome profiling of ovaries in aged mice administered with Samul-tang
2024-04-30 | GSE264413 | GEO
Genomics DBVDC
| PRJEB30571 | ENA
Transcriptomics High resolution time-course data of regenerating Dorsal Root Ganglion neurons
2007-07-09 | GSE5762 | GEO
Transcriptomics Silencing core spliceosome Sm gene expression induces a cytotoxic splicing switch in the proteasome subunit beta 3 mRNA in non-small cell lung cancer cells
2020-06-27 | GSE153332 | GEO
Genomics Coemansia sp. RSA 2671 isolate:RSA 2671
| PRJNA581570 | ENA
Genomics
| PRJNA693436 | ENA