Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling of mouse liver following high fat and normal diets to study insulin resistance and obesity

ABSTRACT: Gene transcription profiling in liver following high fat versus normal diet in C57/Bl6 mice. Characterisation of molecular mechanisms of in vivo insulin action in mouse models of experimentally induced Insulin Resistance. Switched the diet after mice are 5 weeks old, then sampled at 8 days, 3 weeks and 15 weeks.

ORGANISM(S): Mus musculus

SUBMITTER: Xinzhong Li

PROVIDER: E-BAIR-10 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Transcription profiling of muscle cells in mice at different different time points following muscle and normal diets to study insulin resistance and obesty

Project description:Gene transcription profiling in muscle following muscle versus normal diet in C57/Bl6 mice. Switched the diet when mice were 5 weeks old, then sampled at 8 days, 3 weeks and 15 weeks.

2013-01-30 | E-BAIR-11 | biostudies-arrayexpress

Transcription profiling of epidydimal fat pads in mice following high fat and normal diets to study insulin resistance and obesity

Project description:Gene transcription profiling in Epidydimal fat pad (EPD) following High fat versus normal diet in C57/Bl6 mice. Characterisation of molecular mechanisms of in vivo insulin action in mouse models of experimentally induced Insulin resistance. Switched the diet when mice were 5 weeks old, then sampled at 8 days.

2013-01-30 | E-BAIR-12 | biostudies-arrayexpress

Transcription profiling of epidydimal fat pads in mice at different time points following high fat and normal diets to study insulin resistance and obesity

Project description:Gene transcription profiling in Epidydimal fat pad (EPD) following High fat versus normal diet in C57/Bl6 mice. The diet was switched when mice were 5 weeks old, then samples taken at 2 days, 8 days, 3 weeks and 15 weeks.

2013-01-30 | E-BAIR-9 | biostudies-arrayexpress

Transcription profiling of mouse H-2Kb muscle cells treated with metformin (2mM) or insulin (100nM) for 0, 2 or 12 hours

Project description:The basic design of the experiment is as described in Fryer et al.(2000)Diabetes 49:1978, and is similar to proto-BAIR (EXP_BAIR_0603_02). H-2Kb muscle cells were treated with metformin (2mM) or insulin (100nM) for 0, 2 or 12 hours.

2022-11-23 | E-BAIR-7 | biostudies-arrayexpress

Transcription profiling of mouse finally differentiated 3T3-L1 adipocytes treated with insulin (0 or 100nM)or metformin (0 or 2mM)for 2 and 12 hours

Project description:Finally differentiated 3T3-L1 adipocytes are treated with insulin (0 or 100nM)or metformin (0 or 2mM)for 2 and 12 hours to understand insulin and metformin(an anti-diabetic drug commonly applied for Non-Insulin Dependent Diabetes Mellitus)action in adipose tissues.

2013-01-30 | E-BAIR-8 | biostudies-arrayexpress

Transcription profiling of muscle tissue in eight week old Insulin Receptor Substrate-2 (IRS-2) knock-out mice

Project description:Mice which lack IRS-2, develop insulin resistance. Comparison between muscle tissue from 8 week IRS2-KO and wild type mice.

2012-01-01 | E-BAIR-6 | biostudies-arrayexpress

Transcription profiling of skeletal muscle tissue from wild type and RIP140-null mice fed a normal or high-fat diet

Project description:Mice which lack transcriptional corepressor RIP140 show muscle fibre-type switching and increased metabolic gene expression. Comparison between skeletal muscle tissue from wild type and RIP140-null mice fed normal or high-fat diet. Switched the diet when mice were 1 month old, then sampled at 3 months.

2022-11-23 | E-BAIR-13 | biostudies-arrayexpress

Transcription profiling of white adipose tissue in eight week old Insulin Receptor Substrate-2 (IRS-2) knock out mice

Project description:Mice which lack IRS-2, develop insulin resistance. Comparison between white adipose tissue from 8 week old IRS-2 KO and wild type mice. Processed data is not included for this experiment and therefore these data are not MIAME compliant

2012-01-01 | E-BAIR-2 | biostudies-arrayexpress

Transcription profiling of muscle tissue in five week old Insulin Receptor Substrate-2 (IRS-2) KO mice

Project description:Mice which lack IRS-2, develop insulin resistance. Comparison between muscle tissue from 5 week old IRS-2 KO mice and wild type.

2012-01-01 | E-BAIR-5 | biostudies-arrayexpress

Transcription profiling of liver tissue in five week old Insulin Receptor Substrate-2 (IRS-2) knock out mice

Project description:Mice which lack IRS-2, develop insulin resistance. Comparison between liver tissue from 5 weeks old IRS-2 KO mice and wild type.

2012-01-01 | E-BAIR-3 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data