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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Staphylococcus aureus CC398 Clade Associated with Human-to-Human Transmission

ABSTRACT: Staphylococcus aureus clonal complex 398 (CC398) isolates colonize livestock and can spread to human contacts. Genetic analysis of isolates epidemiologically associated with human-to-human, but not livestock, transmission in multiple countries and continents identified a common clade that was negative for tet(M) and positive for bacteriophage 3. Another group of human-to-human-transmitted isolates belonged to the common livestock-associated clade but had acquired a unique φ7 bacteriophage. [Data is also available from http://bugs.sgul.ac.uk/E-BUGS-124]

ORGANISM(S): Staphylococcus aureus

SUBMITTER: Adam Witney

PROVIDER: E-BUGS-124 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Staphylococcus aureus CC398 clade associated with human-to-human transmission.

McCarthy Alex J AJ van Wamel Willem W Vandendriessche Stien S Larsen Jesper J Denis Olivier O Garcia-Graells Cristina C Uhlemann Ann-Catrin AC Lowy Franklin D FD Skov Robert R Lindsay Jodi A JA

Applied and environmental microbiology 20121005 24

Staphylococcus aureus clonal complex 398 (CC398) isolates colonize livestock and can spread to human contacts. Genetic analysis of isolates epidemiologically associated with human-to-human, but not livestock, transmission in multiple countries and continents identified a common clade that was negative for tet(M) and positive for bacteriophage 3. Another group of human-to-human-transmitted isolates belonged to the common livestock-associated clade but had acquired a unique 7 bacteriophage. ...[more]

PMID: 23042163

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