Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling by array of Staphylococcus aureus MRSA-252 treated with ranalexin


ABSTRACT: Data is also available from BuG@Sbase

INSTRUMENT(S): Bioanalyser

ORGANISM(S): Staphylococcus aureus

SUBMITTER: unknown unknown 

PROVIDER: E-BUGS-65 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus.

Overton Ian M IM   Graham Shirley S   Gould Katherine A KA   Hinds Jason J   Botting Catherine H CH   Shirran Sally S   Barton Geoffrey J GJ   Coote Peter J PJ  

BMC systems biology 20110512


<h4>Background</h4>Staphylococcus aureus is a major human pathogen and strains resistant to existing treatments continue to emerge. Development of novel treatments is therefore important. Antimicrobial peptides represent a source of potential novel antibiotics to combat resistant bacteria such as Methicillin-Resistant Staphylococcus aureus (MRSA). A promising antimicrobial peptide is ranalexin, which has potent activity against Gram-positive bacteria, and particularly S. aureus. Understanding mo  ...[more]

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