Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Peter White
PROVIDER: E-CBIL-16 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Proceedings of the National Academy of Sciences of the United States of America 20040818 35
CCAAT enhancer-binding protein beta (C/EBPbeta), a basic-leucine zipper transcription factor, is an important effector of signals in physiologic growth and cancer. The identification of direct C/EBPbeta targets in vivo has been limited by functional compensation by other C/EBP family proteins and the low stringency of the consensus sequence. Here we use the combined power of expression profiling and high-throughput chromatin immunoprecipitation to identify direct and biologically relevant target ...[more]