Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Ronald Kahn
PROVIDER: E-CBIL-26 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Tseng Yu-Hua YH Butte Atul J AJ Kokkotou Efi E Yechoor Vijay K VK Taniguchi Cullen M CM Kriauciunas Kristina M KM Cypess Aaron M AM Niinobe Michio M Yoshikawa Kazuaki K Patti Mary Elizabeth ME Kahn C Ronald CR
Nature cell biology 20050515 6
The insulin/IGF-1 (insulin-like growth factor 1) signalling pathway promotes adipocyte differentiation via complex signalling networks. Here, using microarray analysis of brown preadipocytes that are derived from wild-type and insulin receptor substrate (Irs) knockout animals that exhibit progressively impaired differentiation, we define 374 genes/expressed-sequence tags whose expression in preadipocytes correlates with the ultimate ability of the cells to differentiate. Many of these genes, inc ...[more]