Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Klaus Kaestner
PROVIDER: E-CBIL-34 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hardy Olga T OT Hohmeier Hans E HE Becker Thomas C TC Manduchi Elisabetta E Doliba Nicolai M NM Gupta Rana K RK White Peter P Stoeckert Christian J CJ Matschinsky Franz M FM Newgard Christopher B CB Kaestner Klaus H KH
Molecular endocrinology (Baltimore, Md.) 20061221 3
Recent advances in functional genomics afford the opportunity to interrogate the expression profiles of thousands of genes simultaneously and examine the function of these genes in a high-throughput manner. In this study, we describe a rational and efficient approach to identifying novel regulators of insulin secretion by the pancreatic beta-cell. Computational analysis of expression profiles of several mouse and cellular models of impaired insulin secretion identified 373 candidate genes involv ...[more]