Transcription profiling of pig endothelial cells from animials fed high or low cholesterol diet shows brief hypercholesterolemia induces side-specific protective changes in pig aortic valve endothelia

ABSTRACT: The study demonstrates (i) spatial heterogeneity of endothelial responses to hypercholesterolemia in the aortic valve, (ii) that endothelial metabolism is not dysfunctional in early focal lipid insudation, and (iii) that protective endothelial pathways induced by hypercholesterolemia may initially inhibit the onset of AVS in regions most susceptible.

ORGANISM(S): Sus scrofa

SUBMITTER: Peter Davies 

PROVIDER: E-CBIL-47 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress