Transcription profiling of injured retinas from male Sprague-Dawley rats at 4 hours, 1, 3, 7 and 30 days post-injury
Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Eldon Geisert
PROVIDER: E-GEOD-1001 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Temporal changes in gene expression after injury in the rat retina.
Vázquez-Chona Félix F Song Bong K BK Geisert Eldon E EE
Investigative ophthalmology & visual science 20040801 8
<h4>Purpose</h4>The goal of this study was to define the temporal changes in gene expression after retinal injury and to relate these changes to the inflammatory and reactive response. A specific emphasis was placed on the tetraspanin family of proteins and their relationship with markers of reactive gliosis.<h4>Methods</h4>Retinal tears were induced in adult rats by scraping the retina with a needle. After different survival times (4 hours, and 1, 3, 7, and 30 days), the retinas were removed, a ...[more]
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