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Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy

ABSTRACT: Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy Keywords = Diabetes Keywords = kidney Keywords = glomeruli Keywords: other. This dataset is part of the TransQST collection.

ORGANISM(S): Homo sapiens

SUBMITTER: Hans Baelde

PROVIDER: E-GEOD-1009 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy.

Baelde Hans J HJ Eikmans Michael M Doran Peter P PP Lappin David W P DW de Heer Emile E Bruijn Jan A JA

American journal of kidney diseases : the official journal of the National Kidney Foundation 20040401 4

<h4>Background</h4>Diabetic nephropathy (DN) is a frequent complication in patients with diabetes mellitus. To find improved intervention strategies in this disease, it is necessary to investigate the molecular mechanisms involved. To obtain more insight into processes that lead to DN, messenger RNA expression profiles of diabetic glomeruli and glomeruli from healthy individuals were compared.<h4>Methods</h4>Two morphologically normal kidneys and 2 kidneys from patients with DN were used for the ...[more]

PMID: 15042541

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