Unknown,Transcriptomics,Genomics,Proteomics

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The EBV latent membrane protein 1 (LMP1) induces cellular microRNA-146a, a modulator of lymphocyte signaling pathways


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE10057: The Epstein-Barr Virus latent membrane protein 1 (LMP1) induces cellular microRNA146a GSE10105: Alteration of microRNA gene expression by EBV encoded LMP1 oncogene Keywords: SuperSeries Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Erik Flemington 

PROVIDER: E-GEOD-10107 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Epstein-Barr virus latent membrane protein 1 induces cellular MicroRNA miR-146a, a modulator of lymphocyte signaling pathways.

Cameron Jennifer E JE   Yin Qinyan Q   Fewell Claire C   Lacey Michelle M   McBride Jane J   Wang Xia X   Lin Zhen Z   Schaefer Brian C BC   Flemington Erik K EK  

Journal of virology 20071205 4


The Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) is a functional homologue of the tumor necrosis factor receptor family and contributes substantially to the oncogenic potential of EBV through activation of nuclear factor kappaB (NF-kappaB). MicroRNAs (miRNAs) are a class of small RNA molecules that are involved in the regulation of cellular processes such as growth, development, and apoptosis and have recently been linked to cancer phenotypes. Through miRNA microarray analys  ...[more]

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