Evidence of the role of tick subolesin in gene expression
Ontology highlight
ABSTRACT:
ORGANISM(S): Ixodes scapularis
SUBMITTER: Patricia Ayoubi
PROVIDER: E-GEOD-10222 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Evidence of the role of tick subolesin in gene expression.
de la Fuente José J Maritz-Olivier Christine C Naranjo Victoria V Ayoubi Patricia P Nijhof Ard M AM Almazán Consuelo C Canales Mario M Pérez de la Lastra José M JM Galindo Ruth C RC Blouin Edmour F EF Gortazar Christian C Jongejan Frans F Kocan Katherine M KM
BMC genomics 20080802
<h4>Background</h4>Subolesin is an evolutionary conserved protein that was discovered recently in Ixodes scapularis as a tick protective antigen and has a role in tick blood digestion, reproduction and development. In other organisms, subolesin orthologs may be involved in the control of developmental processes. Because of the profound effect of subolesin knockdown in ticks and other organisms, we hypothesized that subolesin plays a role in gene expression, and therefore affects multiple cellula ...[more]
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