Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Henry Kaminski
PROVIDER: E-GEOD-1025 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Porter John D JD Merriam Anita P AP Leahy Patrick P Gong Bendi B Khanna Sangeeta S
Human molecular genetics 20030801 15
Although dystrophin mutations are the proximate cause of Duchenne muscular dystrophy (DMD), interactions among heterogeneous downstream mechanisms may be key phenotypic determinants. Temporal gene expression profiling was used to identify and correlate diverse transcriptional patterns to one another and to the disease course, for both affected and spared muscle groups, in postnatal day 7-112 dystrophin-deficient (mdx) mice. While 719 transcripts were differentially expressed at one or more ages ...[more]