Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling of human pediatric malignant germ cell tumors


ABSTRACT: To compare the transcriptome profiles of the two principal histological variants of malignant germ cell tumor that occur in childhood Experiment Overall Design: Here, we analyzed the global gene expression profiles of 27 pediatric MGCTs from the two principal histologies (18 yolk sac tumors [YSTs] and 9 seminomas).

ORGANISM(S): Homo sapiens

SUBMITTER: Roger David Palmer 

PROVIDER: E-GEOD-10615 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications


Malignant germ cell tumors (GCT) of childhood are rare and heterogeneous neoplasms thought to arise from primordial germ cells. They vary substantially in their natural history and show important clinical differences from their adult counterparts. To address the biological basis for these observations, we have undertaken a comprehensive analysis of global gene expression patterns in pediatric malignant GCTs and compared these findings with published data on adult testicular GCTs (TGCT). Our stud  ...[more]

Similar Datasets

2022-10-13 | PXD031329 | Pride
2022-12-07 | E-MTAB-11673 | biostudies-arrayexpress
2011-09-01 | GSE30244 | GEO
2021-05-05 | GSE157140 | GEO
2011-08-31 | E-GEOD-30244 | biostudies-arrayexpress
2023-03-01 | E-MTAB-10888 | biostudies-arrayexpress
2023-03-01 | E-MTAB-10552 | biostudies-arrayexpress
2009-12-28 | GSE10113 | GEO
2023-11-01 | GSE188276 | GEO
2015-12-31 | E-GEOD-69204 | biostudies-arrayexpress