Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Min Joo Lee
PROVIDER: E-GEOD-11053 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Biochemical and biophysical research communications 20070228 1
The Mxi1 proteins are biochemical and biological antagonists of c-myc oncoprotein. It has been reported that the overexpression pattern of c-myc might be similar to a molecular feature of early and late stages of human autosomal dominant polycystic kidney disease. We identified the cyst phenotype in Mxi1-deficient mice aged 6-12 months using H&E staining. Some chemokines containing a protein domain similar to human IL-8, which is associated with the inflammatory response, were subsequently selec ...[more]