Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Molecular basis of species-specific variation in beak morphology


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE11027: Chicken versus Quail GSE11028: Duck versus Chicken GSE11029: Duck versus Quail GSE11030: Intra-species comparisons Keywords: SuperSeries Refer to individual Series

ORGANISM(S): Gallus gallus

SUBMITTER: Kara Powder 

PROVIDER: E-GEOD-11099 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Comparative gene expression analysis of avian embryonic facial structures reveals new candidates for human craniofacial disorders.

Brugmann S A SA   Powder K E KE   Young N M NM   Goodnough L H LH   Hahn S M SM   James A W AW   Helms J A JA   Lovett M M  

Human molecular genetics 20091216 5


Mammals and birds have common embryological facial structures, and appear to employ the same molecular genetic developmental toolkit. We utilized natural variation found in bird beaks to investigate what genes drive vertebrate facial morphogenesis. We employed cross-species microarrays to describe the molecular genetic signatures, developmental signaling pathways and the spectrum of transcription factor (TF) gene expression changes that differ between cranial neural crest cells in the developing  ...[more]

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