Unknown,Transcriptomics,Genomics,Proteomics

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Gene expression data from human data of different types of renal tumors and normal kidneys


ABSTRACT: Identification and evaluation of specific molecular markers is of great importance for reliable diagnostics and outcome prediction of renal neoplasms Using the Affymetrix microarray, we established the gene expression signatures of normal kidneys and different types of renal tumors. Keywords: Several different biological groups, several samples per group We analysed several arrays per specific type of renal tumor and normal kidney tissues. This dataset is part of the TransQST collection.

ORGANISM(S): Homo sapiens

SUBMITTER: Dmitry Zubakov 

PROVIDER: E-GEOD-11151 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Gene expression profiling of chromophobe renal cell carcinomas and renal oncocytomas by Affymetrix GeneChip using pooled and individual tumours.

Yusenko Maria V MV   Zubakov Dmitry D   Kovacs Gyula G  

International journal of biological sciences 20090729 6


Due to overlapping morphology, malignant chromophobe renal cell carcinomas (RCC) and benign renal oncocytomas (RO) may pose a diagnostic problem. In the present study, we have applied different algorithms to evaluate the data sets obtained by hybridisation of pooled and also individual samples of renal cell tumours (RCT) onto two different gene expression platforms. The two approaches revealed high similarities in the gene expression profiles of chromophobe RCCs and ROs but also some differences  ...[more]

Publication: 1/3

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