Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Michael Rudnicki
PROVIDER: E-GEOD-11513 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Rudnicki Michael M Perco Paul P Enrich Julia J Eder Susanne S Heininger Dorothea D Bernthaler Andreas A Wiesinger Martin M Sarközi Rita R Noppert Susie-Jane SJ Schramek Herbert H Mayer Bernd B Oberbauer Rainer R Mayer Gert G
Laboratory investigation; a journal of technical methods and pathology 20090112 3
Proteinuria, inflammation, chronic hypoxia, and rarefaction of peritubular capillaries contribute to the progression of renal disease by affecting proximal tubular epithelial cells (PTECs). To study the transcriptional response that separates patients with a stable course from those with a progressive course of disease, we isolated PTECs by laser capture microdissection from cryocut tissue sections of patients with proteinuric glomerulopathies (stable n=20, progressive n=11) with a median clinic ...[more]