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Transcription profiling of mouse Evi-1 deleted hematopoietic stem cells

ABSTRACT: To identify the target genes of Evi-1 in hematopoietic stem cells (HSCs), we carried out genome-wide transcriptional analysis using wild-type and Evi-1-deleted HSCs. Experiment Overall Design: Lineage(-), Sca-1(+), c-Kit(+) cells derived from Evi-1(flox/flox) mice were transduced with GFP or Cre-GFP expressing retroviruses. GFP(+) cells were sorted and and analyzed by AffymetrixÂ® Mouse Genome 430 2.0 ArrayÂ® for gene expression. Two independent experiments were performed.

ORGANISM(S): Mus musculus

SUBMITTER: Susumu Goyama

PROVIDER: E-GEOD-11557 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Effect of Evi-1 deletion in hematopoietic stem cells

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