Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Jennifer Pietenpol
PROVIDER: E-GEOD-11672 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Molecular and cellular biology 20080804 19
Although genomic technologies have advanced the characterization of gene regulatory networks downstream of transcription factors, the identification of pathways upstream of these transcription factors has been more challenging. In this study we present a gene signature-based approach for connecting signaling pathways to transcription factors, as exemplified by p73. We generated a p73 gene signature by integrating whole-genome chromatin immunoprecipitation and expression profiling. The p73 signat ...[more]