Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: D Stephen Charnock-Jones
PROVIDER: E-GEOD-11691 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
The American journal of pathology 20080807 3
The pathophysiology of endometriosis remains unclear but involves a complex interaction between ectopic endometrium and host peritoneal tissues. We hypothesized that disruption of this interaction would suppress endometriotic lesion formation. We hoped to delineate the molecular and cellular dialogue between ectopic human endometrium and peritoneal tissues in nude mice as a first step toward testing this hypothesis. Human endometrium was xenografted into nude mice, and the resulting lesions were ...[more]