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Study of the response of Aspergillus niger to three levels of ambient pH

ABSTRACT: The multiple modes of response to ambient pH were explored and new regulatory structures determined. Biological triplicates from the mid-exponential growth phase of controlled bioreactor batch-cultivations of A. niger.

ORGANISM(S): Aspergillus niger

SUBMITTER: Mikael Andersen

PROVIDER: E-GEOD-11725 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Systemic analysis of the response of Aspergillus niger to ambient pH.

Andersen Mikael R MR Lehmann Linda L Nielsen Jens J

Genome biology 20090501 5

<h4>Background</h4>The filamentous fungus Aspergillus niger is an exceptionally efficient producer of organic acids, which is one of the reasons for its relevance to industrial processes and commercial importance. While it is known that the mechanisms regulating this production are tied to the levels of ambient pH, the reasons and mechanisms for this are poorly understood.<h4>Methods</h4>To cast light on the connection between extracellular pH and acid production, we integrate results from two g ...[more]

PMID: 19409083

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