Ontology highlight
ABSTRACT:
ORGANISM(S): Listeria monocytogenes
SUBMITTER: Regina Stoll
PROVIDER: E-GEOD-12143 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Stoll Regina R Mertins Sonja S Joseph Biju B Müller-Altrock Stefanie S Goebel Werner W
Microbiology (Reading, England) 20081201 Pt 12
PrfA is the major transcriptional activator of most virulence genes of Listeria monocytogenes. Its activity is modulated by a variety of culture conditions. Here, we studied the PrfA activity in the L. monocytogenes wild-type strain EGD and an isogenic prfA deletion mutant (EGDDeltaprfA) carrying multiple copies of the wild-type prfA or the mutant prfA* gene (strains EGDDeltaprfApPrfA and EGDDeltaprfApPrfA*) in response to growth in brain heart infusion (BHI), Luria-Bertani broth (LB) or a defin ...[more]