Transcription profiling of human bone marrow derived and trabecular bone osteogenic cells - 0
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Lourdes Osaba
PROVIDER: E-GEOD-12267 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Gene expression patterns related to osteogenic differentiation of bone marrow-derived mesenchymal stem cells during ex vivo expansion.
Granchi Donatella D Ochoa Gorka G Leonardi Elisa E Devescovi Valentina V Baglìo Serena Rubina SR Osaba Lourdes L Baldini Nicola N Ciapetti Gabriela G
Tissue engineering. Part C, Methods 20100601 3
Bone marrow is commonly used as a source of adult multipotent mesenchymal stem cells (MSCs), defined for their ability to differentiate in vitro into multiple lineages. The ex vivo-expanded MSCs are currently being evaluated as a strategy for the restoration of function in damaged skeletal tissue, both in cell therapy and tissue engineering applications. The aim of this study was to define gene expression patterns underlying the differentiation of MSCs into mature osteoblasts during the expansio ...[more]
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