Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling of rat pineal gland, Expt B


ABSTRACT: Biological processes are optimized by circadian and circannual biological timing systems. In vertebrates, the pineal gland plays an essential role in these systems by converting time into a hormonal signal, melatonin; in all vertebrates, circulating melatonin is elevated at night, independent of lifestyle. We have analyzed the rat pineal transcriptome at mid-day and mid-night to identify genes that exhibit night/day changes in expression. Experiment Overall Design: Rat pineal glands were obtained at mid-day and mid-night for RNA extraction and hybridization to Affymetrix microarrays. Triplicates of pooled pineal glands were analyzed at each timepoint. A similar set of samples was taken from a transgenic rat line (DN-Fra-2; Smith et al. (2001) Mol. Cell. Biol. 21, 3704-3713).

ORGANISM(S): Rattus norvegicus

SUBMITTER: David Klein 

PROVIDER: E-GEOD-12342 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2009-01-25 | E-GEOD-12341 | biostudies-arrayexpress
2009-01-27 | E-GEOD-12343 | biostudies-arrayexpress
2009-01-15 | GSE12342 | GEO
2009-01-15 | GSE12343 | GEO
2009-01-15 | GSE12341 | GEO
2015-03-23 | GSE45654 | GEO
2020-03-03 | GSE146193 | GEO
2014-10-24 | E-GEOD-46127 | biostudies-arrayexpress
2018-10-05 | GSE115723 | GEO
2009-10-30 | E-GEOD-13371 | biostudies-arrayexpress