Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Nicole Ludwig
PROVIDER: E-GEOD-12530 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Keller Andreas A Ludwig Nicole N Backes Christina C Romeike Bernd F M BF Comtesse Nicole N Henn Wolfram W Steudel Wolf-Ingo WI Mawrin Christian C Lenhof Hans-Peter HP Meese Eckart E
International journal of cancer 20090101 2
Genome-wide expression signatures improve the understanding of tumor biology. We performed expression profiling of 24 meningioma including 8 of each WHO grade and 2 dura controls analyzing 55.000 transcripts including 18.300 known genes. We compared expression in meningioma vs. dura, expression of low grade (WHO I) vs. higher-grade (WHO II and WHO III) tumors and expression of meningothelial and syncytial meningioma vs. fibroblastic meningioma. Overall expression was significantly decreased in m ...[more]