Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Global Transcription Profiling and Virulence Potential of Streptococcus pneumoniae after Serial Passage

ABSTRACT: Alterations in global transcriptional profiles of S. pneumoniae 6304 serotype 4 after 50 passages (50P) and 100 passages (100P) on laboratory media Keywords: Adaptation to unique growth environment Three conditions experiment: Control, single passage strain (1P), 2 biological replicates Experimental 50 passage strain (50P), 2 biological replicates Experimental 100 passage strain (100P), 2 biological replicates All strains independently grown and harvested at OD600 ~ 0.5. Four spot replicates per array.

ORGANISM(S): Streptococcus pneumoniae

SUBMITTER: Utpal Pandya

PROVIDER: E-GEOD-12607 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Global transcription profiling and virulence potential of Streptococcus pneumoniae after serial passage.

Pandya Utpal U Sinha Mala M Luxon Bruce A BA Watson David A DA Niesel David W DW

Gene 20090503 1-2

Streptococcus pneumoniae, a facultative human pathogen associated with wide variety of diseases, such as pneumonia, meningitis, sepsis and otitis media. Factors involved in the initial colonization, survival and etiology of this commensal bacteria in the human host from the ex vivo environment is still not clearly understood. Here, we report alterations in global transcriptional profiles of S. pneumoniae 6304 serotype 4 after 50 passages (50P) and 100 passages (100P) on laboratory media to bette ...[more]

PMID: 19397959

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Dataset Information

Global Transcription Profiling and Virulence Potential of Streptococcus pneumoniae after Serial Passage

Publications

Global transcription profiling and virulence potential of Streptococcus pneumoniae after serial passage.

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