Trap-80-dependence of TNF-alpha-induced genes

ABSTRACT: In fibroblasts, p65-dependent genes can be sub-divided, depending on whether they are Trap-80-dependent or -independent. To examine the generality of this grouping, we performed a microarray analysis of wild-type and Trap-80 knock-down fibroblasts, before and after stimulation of NF-kappaB activity using TNF-alpha. RNA was extracted from three independent cultures of wild-type and Trap-80 knock-down fibroblasts, before and after stimulation for 1 hour with 5ng/ml TNF-alpha. The unstimulated and stimulated wild-type samples, and the stimulated Trap-80 knock-down samples, were used for microarray analysis.

ORGANISM(S): Mus musculus

SUBMITTER: Gioacchino Natoli 

PROVIDER: E-GEOD-12697 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress