Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling of mouse cornea overexpressing PITX2A vs. wild type eyes

ABSTRACT: Mice over-expressing human PITX2A in cornea by the keratocan upstream; regulatory sequences. Normalization procedure:; Data normalized to spikes. Values below 0.01 were set to 0.01. All of the genes in each sample were divided by the median of a user specified list of positive control genes (chip-to-chip normalization).

ORGANISM(S): Mus musculus

SUBMITTER: Tord Hjalt

PROVIDER: E-GEOD-1283 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

KPAW and wild type eyes

Project description:Mice over-expressing human PITX2A in cornea by the keratocan upstream regulatory sequences. Normalization procedure: Data normalized to spikes. Values below 0.01 were set to 0.01. All of the genes in each sample were divided by the median of a user specified list of positive control genes (chip-to-chip normalization). Keywords: repeat sample

2005-04-06 | GSE1283 | GEO

Auricularia cornea

Project description:Auricularia cornea overview

| PRJNA388830 | ENA

Calocera cornea

Project description:Calocera cornea overview

| PRJNA251446 | ENA

Auricularia cornea

Project description:Auricularia cornea Genome sequencing

| PRJNA903786 | ENA

Auricularia cornea

Project description:Auricularia cornea Genome sequencing

| PRJNA401993 | ENA

Auricularia cornea

Project description:Auricularia cornea Genome sequencing

| PRJNA503952 | ENA

Auricularia cornea

Project description:Auricularia cornea Genome sequencing

| PRJNA402005 | ENA

Auricularia cornea

Project description:Auricularia cornea Raw sequence reads

| PRJNA853570 | ENA

Single cell RNA-seq of human cornea organoids identifies cell fates of a developing immature cornea

Project description:The cornea is a protective and refractive barrier in the eye crucial for vision. Understanding the human cornea in health, disease and cell-based treatments can be greatly advanced with cornea organoids developed in culture from induced pluripotent stem cells. While a limited number of studies have investigated the single-cell transcriptomic composition of the human cornea, its organoids have not been examined similarly. Here we elucidated the transcriptomic cell fate map of 4-month-old human cornea organoids and human donor corneas. The organoids harbor cell clusters that resemble cells of the corneal epithelium, stroma and endothelium with sub-populations that capture signatures of early developmental states. Unlike the adult cornea where the largest cell population is stromal, the organoids contain large proportions of epithelial and endothelial-like cells. These corneal organoids offer a three-dimensional model to study corneal diseases and integrated responses of different cell types.

2023-01-25 | GSE218123 | GEO

Auricularia cornea

Project description:Auricularia cornea Transcriptome or Gene expression

| PRJNA388738 | ENA