Ontology highlight
ABSTRACT:
ORGANISM(S): Escherichia coli
SUBMITTER: Toru Tobe
PROVIDER: E-GEOD-12903 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Nakanishi Noriko N Tashiro Kosuke K Kuhara Satoru S Hayashi Tetsuya T Sugimoto Nakaba N Tobe Toru T
Microbiology (Reading, England) 20090201 Pt 2
Enterohaemorrhagic Escherichia coli (EHEC) colonizes and proliferates at the mucosal surface, inducing severe diarrhoea. Short-chain fatty acids (SCFAs) are abundant in the intestine owing to the metabolic activity of microflora, and are important for colonic health. We found that, although a high concentration of SCFAs inhibited the growth of EHEC, at low concentrations, the SCFAs markedly enhanced the expression of the virulence genes required for cell adherence and the induction of attaching ...[more]