Profiling of adipose tissue from the F2 M16xICR mouse cross.
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Radu Dobrin
PROVIDER: E-GEOD-13746 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease.
Dobrin Radu R Zhu Jun J Molony Cliona C Argman Carmen C Parrish Mark L ML Carlson Sonia S Allan Mark F MF Pomp Daniel D Schadt Eric E EE
Genome biology 20090522 5
<h4>Background</h4>Obesity is a particularly complex disease that at least partially involves genetic and environmental perturbations to gene-networks connecting the hypothalamus and several metabolic tissues, resulting in an energy imbalance at the systems level.<h4>Results</h4>To provide an inter-tissue view of obesity with respect to molecular states that are associated with physiological states, we developed a framework for constructing tissue-to-tissue coexpression networks between genes in ...[more]
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