Transcription profiling of Xenopus embryonic posterior mesoderm controls and Derriere depleted embryos

ABSTRACT: Left-right axis determination is a fundamental and conserved developmental process, with consequences for human pathology. At the molecular level, this process requires at least two centers of nodal-type TGFbeta signals: the first center, containing nodal/Xn; Microarrays were used to determine differences in gene expression in posterior mesoderm of Xenopus embryos. We compared controls and Derriere depleted embryos. Experiment Overall Design: Microarrays were used to determine differences in gene expression in posterior mesoderm of Xenopus embryos. We compared controls and embryos depleted of Derriere protein using MO oligonucleotides.

ORGANISM(S): Xenopus laevis

SUBMITTER: Ali Brivanlou 

PROVIDER: E-GEOD-13882 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress