Gene expression change caused by CYS4 alleles
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Justin Fay
PROVIDER: E-GEOD-14102 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Dissecting the pleiotropic consequences of a quantitative trait nucleotide.
Kim Hyun Seok HS Huh Juyoung J Fay Justin C JC
FEMS yeast research 20090423 5
The downstream consequences of a single quantitative trait polymorphism can provide important insight into the molecular basis of a trait. However, the molecular consequences of a polymorphism may be complex and only a subset of these may influence the trait of interest. In natural isolates of Saccharomyces cerevisiae, a nonsynonymous polymorphism in cystathione beta-synthase (CYS4) causes a deficiency in both cysteine and glutathione that results in rust-colored colonies and drug-dependent grow ...[more]
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