Ontology highlight
ABSTRACT:
ORGANISM(S): Streptococcus agalactiae
SUBMITTER: Daniel Shelver
PROVIDER: E-GEOD-14259 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Quach Darin D van Sorge Nina M NM Kristian Sascha A SA Bryan Joshua D JD Shelver Daniel W DW Doran Kelly S KS
Journal of bacteriology 20081229 7
Group B Streptococcus (GBS) is major cause of invasive disease in newborn infants and the leading cause of neonatal meningitis. To gain access to the central nervous system (CNS), GBS must not only subvert host defenses in the bloodstream but also invade and survive within brain microvascular endothelial cells (BMEC), the principal cell layer composing the blood-brain barrier (BBB). While several GBS determinants that contribute to the invasion of BMEC have been identified, little is known about ...[more]