Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Comparison of CD4+ T cell function between HIV-1 resistant and HIV-1 susceptible individuals (Immune)


ABSTRACT: Understanding why some indidivual resist HIV-1 infection despite continued exposure is an important goal for vaccine development. We compared CD4+ T cell gene expression at baseline and after antigenic stimulation in HIV-1 resistant commercial sex-workers from Nairobi, Kenya to HIV-1 low-risk negative (non-resistant) non-commercial sex-workers using immune-focused gene expression arrays Keywords: Case-control, disease state analysis CD4+ T cells from both HIV resistant and HIV low-risk negative individuals were isolated from PBMC after 24 hours of culture by negative slelction. Total RNA was isolated and gene expression compared using immune-focused expression arrays.

ORGANISM(S): Homo sapiens

SUBMITTER: Paul McLaren 

PROVIDER: E-GEOD-14279 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2009-01-17 | E-GEOD-14278 | biostudies-arrayexpress
2010-03-02 | GSE14279 | GEO
2010-05-07 | E-GEOD-14280 | biostudies-arrayexpress
2010-03-02 | GSE14278 | GEO
2012-11-11 | GSE33580 | GEO
2010-06-21 | E-GEOD-18468 | biostudies-arrayexpress
2010-06-25 | E-GEOD-14542 | biostudies-arrayexpress
| phs000445.v1.p1 | EGA
2017-02-28 | PXD005234 | Pride
2012-11-20 | E-GEOD-22822 | biostudies-arrayexpress