Reliability and stability of individual differences in gene expression
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Emma Meaburn
PROVIDER: E-GEOD-14844 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Assessing individual differences in genome-wide gene expression in human whole blood: reliability over four hours and stability over 10 months.
Meaburn Emma L EL Fernandes Cathy C Craig Ian W IW Plomin Robert R Schalkwyk Leonard C LC
Twin research and human genetics : the official journal of the International Society for Twin Studies 20090801 4
Studying the causes and correlates of natural variation in gene expression in healthy populations assumes that individual differences in gene expression can be reliably and stably assessed across time. However, this is yet to be established. We examined 4-hour test-retest reliability and 10 month test-retest stability of individual differences in gene expression in ten 12-year-old children. Blood was collected on four occasions: 10 a.m. and 2 p.m. on Day 1 and 10 months later at 10 a.m. and 2 p. ...[more]
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